The most engaging and accessible account of cancer biology which clearly links our understanding of cancer with the development of new therapeutics. Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students. Key features- Describes the theoretical basis of cancer biology and shows how this theory is applied to develop new cancer therapies, giving students a clear appreciation of how theoretical knowledge can be translated into therapeutic strategies- Draws on the latest research in cancer biology- Features a variety of learning features to help students engage with the concepts presented: ‘Pause and think’; ‘How do we know that?’; ‘In the clinic’; self-tests; and activitiesNew to this edition- New themes that weave throughout the book, such as the two-way interactions between the microenvironment and the tumour, systemic effects of cancer, and the role of plasticity and heterogeneity in cancer evolution- Expanded coverage of cancer genomics, including single cell genomics and spatial transcriptomics, highlighted in the concluding chapter- A new feature called ‘In the clinic’ that highlights current or potential applications of cancer biology to clinical practice- Updates on newly approved cancer therapeutics- Includes additional primary data from the literature and key references to provide a resource of up-to-date experimental evidence- Expanded artwork programme and new ‘figure sequences’ (in the enhanced e-book) to help readers understand molecular pathways over timeDigital formats and resourcesThe 6th edition is available for students and institutions to purchase in a variety of formats: the e-book and Science Trove offer a mobile experience and convenient access along with multiple choice questions, audio clips, functionality tools, navigation features and links that offer extra learning support.
